Hexarelin
Hexarelin is a synthetic six-amino-acid peptide that binds the ghrelin receptor (GHS-R1a) to trigger robust, reproducible growth-hormone (GH) pulses and cardioprotective signaling in vitro and in vivo. In cardiac-cell and rodent models, Hexarelin enhances GH and IGF-1 release, supports coronary endothelial function, and models anti-apoptotic pathways. Each 5 mg vial is USA-manufactured, HPLC-verified to ≥ 99% purity, and endotoxin-screened (< 0.1 EU/mg), delivering clean, reliable data for GH-axis and cardiovascular research.
⚠️ Important Disclaimer
For Research Use Only. Not for human consumption or therapeutic treatment.
Pairs well with
Peptides are not ready to use. Must purchase BAC water for reconstitution.
Hexarelin
KEY HIGHLIGHTS
Potent GH Release
Hexarelin peptide induces swift GH peaks within 20–30 minutes, enabling precise mapping of downstream IGF-1 dynamics.
IGF-1 Signaling
Drives reproducible IGF-1 upregulation in hepatocyte and cardiac myocyte assays, supporting anabolic- and cardioprotective studies.
Cardioprotective Modeling
In endothelial-cell cultures, Hexarelin enhances nitric-oxide production and reduces apoptosis under hypoxic stress.
Lean-Tissue Anabolism
In muscle-cell assays, it boosts protein-synthesis markers (e.g., AKT/mTOR), modeling anabolic signaling.
Endocrine Feedback Analysis
Short half-life (~ 45 minutes) allows repeated dosing to dissect somatostatin feedback without receptor desensitization.
Easy Prep & Storage
Reconstitute in sterile or bacteriostatic water; store powder at – 20 °C and solution at 2–8 °C for up to 7 days.
What Is Hexarelin Peptide?
Hexarelin is a synthetic GH-releasing peptide that directly activates the ghrelin receptor (GHS-R1a) on pituitary and cardiac cells. Unlike broader secretagogues, Hexarelin provokes strong, reproducible GH surges and engages cardioprotective pathways, making it an ideal research tool for studying both endocrine and cardiovascular models under tightly controlled laboratory conditions.
Why Choose Hexarelin?
Researchers select Hexarelin when they need a dual-action peptide that delivers both robust GH-release and cardioprotective signaling. Its ability to generate clean GH pulses—without significant cortisol or prolactin spikes—combined with demonstrated benefits in endothelial-cell and hypoxia assays makes it uniquely versatile. Manufactured under ISO-certified conditions and verified to ≥ 99% purity with stringent endotoxin screening, Hexarelin provides reproducible, high-fidelity data for hormone-axis and cardiovascular-health research.
What Sets Hexarelin Apart?
Hexarelin stands out by combining potent GH-axis activation with direct cardiac-cell effects. Its six-residue sequence ensures rapid receptor engagement for growth-hormone release, while also triggering anti-apoptotic and vasodilatory pathways in heart-related models. This unique dual-pathway action—paired with a clean, short-acting profile—allows researchers to dissect endocrine and cardiovascular mechanisms in a single peptide, streamlining study design and enhancing translational relevance.
Hexarelin FAQs
What is Hexarelin peptide used for?
To study GH-release dynamics, IGF-1 signaling, and cardioprotective pathways in cell and animal models.
How quickly does Hexarelin trigger GH?
GH peaks occur within 20–30 minutes after dosing in culture or rodent assays.
What benefits does Hexarelin show in cardiac cells?
Enhances nitric-oxide production and reduces apoptosis under hypoxic stress, modeling cardiac protection.
Does Hexarelin raise IGF-1 levels?
Yes—GH surges induced by Hexarelin lead to consistent IGF-1 increases in hepatic and muscle assays.
What dose range is typical for Hexarelin?
In vitro: 100 nM–1 µM; in vivo rodent: 0.1–1 mg/kg, per protocol.
How is Hexarelin reconstituted?
Dissolve in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC) and mix gently until clear.
What storage conditions are required?
Store lyophilized at – 20 °C; keep reconstituted solution at 2–8 °C and use within 7 days.
Does Hexarelin affect other hormones?
It provokes GH without significant cortisol or prolactin elevation—ensuring GH-axis–specific data.
Can Hexarelin be combined with GHRH analogs?
Yes—commonly co-administered with CJC-1295 No DAC or GHRP-6 for comprehensive GH-axis research.
Where can I buy Hexarelin peptide?
Real Peptides offers ISO-certified, USA-manufactured Hexarelin (5 mg), ≥ 99% purity, and low endotoxin—available for research use only.