MK-677
MK-677 (Ibutamoren) capsules deliver a precise 10 mg dose of this potent, orally active ghrelin-mimetic secretagogue in every tablet—no powder weighing, no guesswork. Ideal for labs studying GH-IGF-1 dynamics, feeding-behavior models, and lean-mass signaling, these 60 capsules are USA-manufactured under GMP, HPLC-verified to ≥ 99% purity, and formulated with only microcrystalline cellulose. The ready-to-use, oral format simplifies dosing protocols and ensures each experiment begins with the exact same peptide dose.
⚠️ Important Disclaimer
For Research Use Only. Not for human consumption or therapeutic treatment.
MK-677
KEY HIGHLIGHTS
GH-Axis Activation
Elicits reproducible rises in GH and IGF-1 levels in rodent plasma assays, modeling endocrine pulses.
Appetite-Regulation Models
Modulates feeding-behavior endpoints in diet-induced obesity (DIO) rodent studies.
Lean-Mass Signaling
Enhances protein-synthesis markers (mTOR, S6K) in myoblast and muscle-cell culture assays.
Metabolic-Health Profiling
Impacts adipocyte glucose uptake and lipolysis markers for a full picture of energy balance.
Oral-Dosing Convenience
Capsules ensure uniform 10 mg doses for gavage or dietary-mix protocols—eliminating weighing errors.
Extended Shelf Life
Ambient-stable formulation retains full activity for up to 18 months, easing inventory management.
What Is MK-677 (Ibutamoren)?
MK-677—also known as Ibutamoren—is a small-molecule ghrelin-receptor agonist that stimulates endogenous growth-hormone (GH) secretion. In preclinical research, MK-677 capsules are used to explore how sustained GH and IGF-1 elevations affect metabolism, muscle signaling, and appetite regulation under controlled, oral-dosing conditions.
Why Choose MK-677 Capsules?
Researchers select MK-677 capsules for their ease of use and translational relevance. The oral-delivery format mirrors human administration routes, while the pre-measured 10 mg dosage ensures every study begins with a consistent peptide amount. Whether mapping GH-axis feedback loops or modeling feeding-behavior changes, MK-677 capsules streamline workflows and boost data reproducibility.
What Sets MK-677 Apart?
Unlike injectable secretagogues, MK-677 capsules offer true oral bioavailability, making them ideal for modeling gastrointestinal absorption and long-term dosing studies. Their high purity and minimal-excipient formulation deliver clean, reliable GH-IGF-1 responses, so you can focus on interpreting metabolic outcomes—without extra handling steps or hormone peaks.
MK-677 FAQs
What is MK-677 (Ibutamoren) used for?
To model growth-hormone (GH) and IGF-1 axis activation, appetite regulation, and metabolic-health endpoints in preclinical studies.
How much MK-677 is in each capsule?
Each oral capsule delivers 10 mg of MK-677 (Ibutamoren).
Can I open MK-677 capsules for in vitro use?
Yes—empty the capsule into buffer or culture medium for precise dosing in cell-based assays.
What rodent dose is typical for MK-677?
Common protocols range from 2–10 mg/kg via oral gavage, adjusted per study design.
What in vitro concentration is recommended?
Researchers often use 100–500 nM in cell-culture assays to probe GH-receptor activity.
How should MK-677 capsules be stored?
Store at room temperature (15–25 °C) in a dry, dark place; capsules remain stable for 18 months.
Why choose capsules over powder for MK-677?
Capsules guarantee uniform 10 mg doses, eliminate weighing variability, and simplify oral-dosing workflows.
Are there any fillers in MK-677 capsules?
Only pharmaceutical-grade microcrystalline cellulose, minimizing assay interference.
Is MK-677 endotoxin-tested?
As a non-peptide, endotoxin testing isn’t applicable; formulation meets microbial-grade standards.
Where can I buy MK-677 Ibutamoren capsules?
Real Peptides offers MK-677 (Ibutamoren) 10 mg capsules (60 ct), USA-manufactured, ≥ 99% purity—strictly for research use only.