Selank Amidate 10mg
Selank Amidate is a modified heptapeptide analog of the natural immunomodulator tuftsin, designed for preclinical studies of anxiolytic effects, cognitive enhancement, and neuroprotective signaling. In rodent behavioral assays and neuronal-culture models, Selank Amidate modulates GABAergic pathways, boosts BDNF expression, and supports stress-resilience research. Each 10 mg vial is USA-manufactured, HPLC-verified to ≥ 99% purity, endotoxin-screened (< 0.1 EU/mg), and formulated exclusively for laboratory investigation.
⚠️ Important Disclaimer
For Research Use Only. Not for human consumption or therapeutic treatment.
Selank Amidate
KEY HIGHLIGHTS
Anxiolytic Signaling
Selank Amidate modulates GABA-A receptor subunits in rodent models, providing a tool for anxiety-related behavior research.
Cognitive Enhancement Modeling
In hippocampal neuron assays, Selank upregulates BDNF and CREB phosphorylation—key markers of learning and memory.
Stress-Resilience Support
Behavioral stress-test protocols (e.g., elevated-plus maze) show reduced anxiety indices following Selank Amidate administration.
Neuroprotective Pathways
Selank peptide reduces glutamate-induced excitotoxicity in cortical neuron cultures, modeling protective mechanisms.
Immune-Neuro Crosstalk
In microglial assays, Selank Amidate downregulates pro-inflammatory cytokines (IL-1β, TNF-α), linking immune modulation to neural health.
Lab-Friendly Prep & Storage
Reconstitute in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC). Store lyophilized at – 20 °C; keep reconstituted peptide at 2–8 °C and use within 7 days to maintain ≥ 98% integrity.
What Is Selank Amidate?
Selank Amidate is a chemically stabilized analog of the endogenous immunoregulatory peptide Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro). By amidating its C-terminus, it gains enhanced resistance to enzymatic degradation, making it ideal for in vitro and in vivo models of anxiety modulation, cognitive function, and neuroinflammation. Researchers leverage Selank Amidate to dissect peptide-driven pathways in brain regions governing stress, memory, and mood.
Why Choose Selank Amidate?
Researchers select Selank Amidate for its dual action on neurochemical and immune pathways. Its proven ability to reduce anxiety-like behaviors, boost neurotrophic factors (BDNF), and modulate cytokine profiles provides a versatile platform for preclinical neuropsychiatric and neurodegenerative research. Manufactured under ISO-certified conditions and verified to ≥ 99% purity by HPLC—with endotoxin < 0.1 EU/mg—Selank Amidate delivers consistent, reproducible outcomes for high-impact cognitive and anxiolytic studies.
What Sets Selank Amidate Apart?
Unlike unmodified peptides, Selank Amidate’s C-terminal amidation confers enhanced metabolic stability and extended half-life in biological models. It uniquely combines anxiolytic and cognitive-enhancing effects with anti-inflammatory properties, allowing simultaneous investigation of mood-behavior and neuroimmune interactions. Its robust performance in both behavioral and cellular assays makes Selank Amidate the go-to peptide for neuro-behavioral, stress, and cognitive research.
Selank Amidate FAQs
What is Selank Amidate peptide?
A stabilized analog of the heptapeptide Selank, used to study anxiety modulation, cognitive function, and neuroimmune signaling in research models.
How does Selank Amidate reduce anxiety in rodents?
By modulating GABA-A receptor activity and neurotrophic signaling pathways, leading to lower anxiety-like behavior in maze and stress assays.
Can Selank peptide enhance memory?
Yes—Selank Amidate upregulates BDNF and CREB phosphorylation in hippocampal cultures, modeling molecular mechanisms of learning and memory.
What research applications use Selank Amidate?
Commonly in anxiety-behavior tests (elevated-plus maze), cognitive-task assays, and neuroinflammation models using microglial cultures.
What concentration is typical for Selank Amidate studies?
In vitro work often uses 100 nM–10 µM; in rodent in vivo assays, doses range 0.1–1 mg/kg, per protocol.
How is Selank Amidate reconstituted?
Dissolve in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC) per your SOP and mix gently until clear.
What storage conditions are required?
Store lyophilized at – 20 °C; keep reconstituted peptide at 2–8 °C and use within 7 days to maintain ≥ 98% integrity.
Does Selank Amidate affect inflammation?
In microglial assays, Selank reduces IL-1β and TNF-α expression, modeling neuroimmune crosstalk in research.
Is Selank Amidate approved for human use?
No—Selank Amidate is strictly for research use only and not approved for human or veterinary application.
Where can I buy Selank Amidate peptide?
Real Peptides offers ISO-certified, USA-manufactured Selank Amidate (10 mg) at ≥ 99% purity and low endotoxin—available for research use only.