VIP

KEY HIGHLIGHTS

Potent Vasodilation Modeling

Activates VPAC receptors on vascular smooth-muscle cells to study vessel-relaxation mechanisms.

Neuroimmune Signaling

Triggers cytokine-modulation pathways in microglia and T-cell assays, ideal for gut-brain and inflammation research.

Gut-Brain Axis Probing

Used in enteric-neuron cultures to map VIP’s role in digestive-tract motility and neuropeptide crosstalk.

Smooth-Muscle Relaxation

Delivers clear, dose-dependent cAMP increases in smooth-muscle assays—perfect for bronchodilation and gut-motility models.

Cell-Survival Support

VIP combats oxidative and inflammatory stress in neuronal and epithelial cells, aiding neuroprotection studies.

Lab-Ready Format

Lyophilized powder—reconstitute in sterile water, store at 2–8 °C, and use within 7 days for consistent activity.

What Is VIP Peptide?

VIP is a 28-amino-acid neuropeptide that naturally regulates blood-vessel tone, immune responses, and digestive-tract signaling. In research, VIP peptide is used to explore vasodilation, neuroimmune interactions, and enteric-nervous-system pathways under controlled lab conditions.

Why Choose VIP?

Choose VIP when you want a versatile peptide that covers vascular, neural, and immune assays in one reagent. Its reliable activation of VPAC receptors delivers reproducible vasodilation, cAMP signaling, and cytokine modulation—so you can compare compounds, map pathways, or screen anti-inflammatory agents with confidence.

What Sets VIP Apart?

Unlike single-pathway agonists, VIP offers multi-system utility—simultaneously engaging vascular, neuronal, and immune cells. Its robust receptor specificity and rapid, dose-dependent action make VIP the go-to peptide for integrated studies of blood-flow regulation, gut-brain communication, and neuroimmune balance.

VIP FAQs

What is VIP peptide used for in research?

To study vasodilation, neuroimmune signaling, and gut-brain axis pathways in cell and animal models.

How quickly does VIP trigger vasodilation?

Smooth-muscle cAMP increases can be measured within 5–15 minutes of dosing.

What concentrations are typical in vitro?

Researchers often use 10–100 nM, adjusted per cell type and endpoint.

Can VIP modulate immune-cell behavior?

Yes—VIP alters cytokine release and T-cell activation in immune-cell assays.

Does VIP affect gut motility?

In enteric-neuron cultures, VIP influences peristalsis markers and ion-channel activity.

How is VIP peptide reconstituted?

Dissolve in Sterile Water for Injection, mix gently, then use immediately or store at 2–8 °C.

What storage conditions are required?

Keep powder at –20 °C; use reconstituted solution within 7 days at 2–8 °C.

Does VIP impact oxidative-stress markers?

VIP supports cell-survival pathways, reducing ROS and apoptosis in neuronal assays.

Is VIP approved for human use?

No—strictly for research use only, not for clinical or veterinary applications.

Where can I buy VIP peptide?

Real Peptides offers ISO-certified, USA-manufactured VIP (5 mg), ≥ 99% purity, and low endotoxin—available for research use only.

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