






Melanotan-1
Melanotan-1 is the classic melanocortin analog that jumps-starts melanin production in melanocyte cultures and preclinical models—perfect for labs dialing in skin-pigmentation pathways. One 10 mg vial delivers a stable, easy-to-use peptide that reliably sparks dose-dependent pigmentation without extra hormonal noise. USA-made, ≥ 99% pure (HPLC), and low-endotoxin (< 0.1 EU/mg), Melanotan-1 gives you fast, crisp melanin-response data every time.
⚠️ Important Disclaimer
For Research Use Only. Not for human consumption or therapeutic treatment.
Melanotan-1
KEY BENEFITS
Reliable Melanin Induction
Sparks melanin synthesis in cultured skin cells, so you get consistent pigmentation curves.
Pigmentation Dose-Response
Shows a clear, concentration-dependent increase in melanin markers for precise assay tuning.
UV-Protection Modeling
Enhances cell resilience under UV stress, enabling robust photoprotection studies.
MC1R-Selective Action
High affinity for the melanocortin-1 receptor ensures focused pigmentation effects without off-target signaling.
Rapid Onset
Observe melanin upregulation within hours, speeding up your screening workflows.
Ready for Lab Use
Lyophilized powder—just reconstitute in sterile water, store at 2–8 °C, and use within 7 days.


What Is Melanotan-1?
Melanotan-1 is a synthetic peptide analog of α-MSH that binds the melanocortin-1 receptor (MC1R) on skin cells to trigger melanin production. Researchers use it to study pigmentation dynamics, UV-response mechanisms, and melanocyte biology with high precision and minimal variability.

Why Choose Melanotan-1?
Pick Melanotan-1 when you need a straightforward pigmentation tool. Its proven ability to induce melanin reliably—without influencing unrelated hormone pathways—makes it ideal for screening sunscreen agents, pigment regulators, and UV-protection compounds in both cell and animal models.

What Sets Melanotan-1 Apart?
Unlike broader melanocortin fragments, Melanotan-1 offers enhanced stability and MC1R specificity, giving you stronger, longer-lasting pigmentation signals. Its simple dosing and clean receptor profile mean fewer variables and more reproducible pigmentation assays.
Melanotan-1 FAQs
What is Melanotan-1 used for in research?
To study melanin production, pigmentation pathways, and UV-protection in cell and animal models.
How quickly does Melanotan-1 work?
Pigmentation markers appear within 4–6 hours in melanocyte cultures.
What concentration should I use?
Typical in vitro ranges are 100 nM–1 µM, adjusted per cell line and endpoint.
Can Melanotan-1 protect cells from UV damage?
Yes—treated cells show enhanced survival and reduced DNA damage under UV stress.
How do I prepare Melanotan-1?
Reconstitute in Sterile Water for Injection, mix gently until clear, then use immediately or store at 2–8 °C.
What storage conditions are required?
Keep powder at –20 °C; use reconstituted solution within 7 days at 2–8 °C.
Does Melanotan-1 affect other hormones?
No—its design ensures MC1R-specific action without cortisol or ACTH spikes.
Can I combine it with UV-filter compounds?
Yes—commonly paired with antioxidants or sunscreen agents for synergistic photoprotection studies.
Is Melanotan-1 approved for clinical use?
No—strictly for research use only, not for therapeutic or cosmetic application.
Where can I buy Melanotan-1 peptide?
Real Peptides offers ISO-certified, USA-manufactured Melanotan-1 (10 mg), ≥ 99% purity, and low endotoxin—available for research use only.