Melanotan-1

KEY BENEFITS

Reliable Melanin Induction

Sparks melanin synthesis in cultured skin cells, so you get consistent pigmentation curves.

Pigmentation Dose-Response

Shows a clear, concentration-dependent increase in melanin markers for precise assay tuning.

UV-Protection Modeling

Enhances cell resilience under UV stress, enabling robust photoprotection studies.

MC1R-Selective Action

High affinity for the melanocortin-1 receptor ensures focused pigmentation effects without off-target signaling.

Rapid Onset

Observe melanin upregulation within hours, speeding up your screening workflows.

Ready for Lab Use

Lyophilized powder—just reconstitute in sterile water, store at 2–8 °C, and use within 7 days.

What Is Melanotan-1?

Melanotan-1 is a synthetic peptide analog of α-MSH that binds the melanocortin-1 receptor (MC1R) on skin cells to trigger melanin production. Researchers use it to study pigmentation dynamics, UV-response mechanisms, and melanocyte biology with high precision and minimal variability.

Why Choose Melanotan-1?

Pick Melanotan-1 when you need a straightforward pigmentation tool. Its proven ability to induce melanin reliably—without influencing unrelated hormone pathways—makes it ideal for screening sunscreen agents, pigment regulators, and UV-protection compounds in both cell and animal models.

What Sets Melanotan-1 Apart?

Unlike broader melanocortin fragments, Melanotan-1 offers enhanced stability and MC1R specificity, giving you stronger, longer-lasting pigmentation signals. Its simple dosing and clean receptor profile mean fewer variables and more reproducible pigmentation assays.

Melanotan-1 FAQs

What is Melanotan-1 used for in research?

To study melanin production, pigmentation pathways, and UV-protection in cell and animal models.

How quickly does Melanotan-1 work?

Pigmentation markers appear within 4–6 hours in melanocyte cultures.

What concentration should I use?

Typical in vitro ranges are 100 nM–1 µM, adjusted per cell line and endpoint.

Can Melanotan-1 protect cells from UV damage?

Yes—treated cells show enhanced survival and reduced DNA damage under UV stress.

How do I prepare Melanotan-1?

Reconstitute in Sterile Water for Injection, mix gently until clear, then use immediately or store at 2–8 °C.

What storage conditions are required?

Keep powder at –20 °C; use reconstituted solution within 7 days at 2–8 °C.

Does Melanotan-1 affect other hormones?

No—its design ensures MC1R-specific action without cortisol or ACTH spikes.

Can I combine it with UV-filter compounds?

Yes—commonly paired with antioxidants or sunscreen agents for synergistic photoprotection studies.

Is Melanotan-1 approved for clinical use?

No—strictly for research use only, not for therapeutic or cosmetic application.

Where can I buy Melanotan-1 peptide?

Real Peptides offers ISO-certified, USA-manufactured Melanotan-1 (10 mg), ≥ 99% purity, and low endotoxin—available for research use only.

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