








GHK-Cu Cosmetic 5mg
GHK-Cu Cosmetic is a specialized form of Copper Tripeptide-1 (Gly-His-Lys) designed for research into dermal rejuvenation, wrinkle-reduction, and follicle-stimulating pathways. In skin-equivalent and hair-follicle models, it enhances collagen synthesis, promotes microvascular health, and activates dermal papilla cells. Each 5 mg vial is USA-manufactured, HPLC-verified to ≥ 99% purity, endotoxin-screened (< 0.1 EU/mg), and supplied with detailed handling guidelines.
⚠️ Important Disclaimer
For Research Use Only. Not for human consumption or therapeutic treatment.
GHK-Cu Cosmetic
KEY HIGHLIGHTS
Collagen & Elastin Synthesis
Boosts Type I/III collagen and elastin production in dermal fibroblast assays, modeling skin-firming and anti-wrinkle effects.
VEGF-Driven Angiogenesis
Elevates VEGF expression and capillary-tube formation in endothelial cultures, supporting microvascular health studies.
Wrinkle-Reduction Modeling
In 3D skin equivalents, reduces simulated wrinkle depth by improving extracellular matrix organization.
Follicle Activation
Stimulates dermal papilla cell proliferation and hair-shaft thickening in ex vivo follicle micro-culture assays.
Anti-Inflammatory Modulation
Downregulates IL-1β and TNF-α in keratinocyte models, providing a tool for inflammation-resolution research.
Lab-Friendly Handling
Reconstitute in SWFI or BAC water; store lyophilized at –20 °C and reconstituted peptide at 2–8 °C for up to 7 days to maintain ≥ 98% integrity.


What Is GHK-Cu Cosmetic?
GHK-Cu Cosmetic is a research-grade Copper Tripeptide-1 variant formulated to target skin and hair-follicle biology. By chelating copper to the Gly-His-Lys sequence, it mimics natural copper-peptide signaling to drive collagen and elastin synthesis, VEGF-mediated angiogenesis, and hair-follicle proliferation. In preclinical assays—both 2D and 3D—it offers a precise tool for studying anti-aging and regenerative mechanisms in epidermal and follicular tissues.

Why Choose GHK-Cu Cosmetic?
Labs select GHK-Cu Cosmetic for its dual potency in skin-matrix remodeling and follicular activation, making it ideal for wrinkle-reduction, scar-healing, and hair-growth studies. Its cosmetic-grade formulation ensures optimal solubility and stability in topical serum and organotypic models. Manufactured under ISO-certified conditions, each batch is tested to ≥ 99% purity, with endotoxin levels below 0.1 EU/mg—guaranteeing reproducible, high-definition data for your dermal and trichology research.

What Sets GHK-Cu Cosmetic Apart?
Unlike generic GHK-Cu, the Cosmetic variant is optimized for topical and ex vivo skin models, with enhanced buffer compatibility and stability in low-pH formulations. It not only upregulates collagen I/III and elastin in dermal fibroblasts but also drives dermal papilla cell proliferation for hair-growth assays. Its proven efficacy in skin-equivalent explants and follicle-microculture sets GHK-Cu Cosmetic apart as the go-to peptide for advanced anti-aging and hair-regeneration research.
GHK-Cu Cosmetic FAQs
What is GHK-Cu Cosmetic peptide?
A Copper Tripeptide-1 variant optimized for skin and hair-follicle research, enhancing collagen, elastin, and follicle cell activity.
How does GHK-Cu Cosmetic support wrinkle reduction?
It upregulates collagen I/III and elastin gene expression in dermal fibroblast assays, modeling anti-wrinkle mechanisms.
Can GHK-Cu Cosmetic promote hair growth?
Yes—studies show it stimulates dermal papilla cell proliferation and increases hair-shaft thickness in follicle culture models.
What concentration is typical for skin-equivalent assays?
Researchers often use 100 nM–5 µM in both 2D fibroblast and 3D skin-equivalent systems.
How is GHK-Cu Cosmetic reconstituted?
Dissolve in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC) at neutral pH, then integrate into your topical formulation or culture media.
What storage conditions are required?
Store lyophilized at –20 °C; keep reconstituted solution at 2–8 °C and use within 7 days to maintain ≥ 98% integrity.
Does GHK-Cu Cosmetic have anti-inflammatory effects?
It downregulates pro-inflammatory cytokines (IL-1β, TNF-α) in keratinocyte models, aiding skin-repair research.
Is GHK-Cu Cosmetic safe for ex vivo skin models?
Yes—its ISO-certified purity (≥ 99%) and low endotoxin level make it ideal for delicate skin and organ-culture assays.
Can GHK-Cu Cosmetic be combined with other actives?
Frequently co-studied with hyaluronic acid, retinoids, or antioxidant peptides to evaluate synergistic anti-aging effects.
Where can I buy GHK-Cu Cosmetic peptide?
Real Peptides offers GHK-Cu Cosmetic made in USA-based ISO-certified labs, verified to ≥ 99% purity and < 0.1 EU/mg endotoxin—available for research use only.