LL-37
LL-37 is a human-derived antimicrobial peptide trusted by labs to model innate-immunity, antimicrobial defense, and wound-healing processes. Each 5 mg vial delivers a ready-to-use peptide that boosts microbial-killing assays, supports cell-migration in scratch-wound models, and activates innate-immune signaling—with no extra compounds or guesswork. Manufactured in the USA, HPLC-verified to ≥ 99% purity, and endotoxin-screened (< 0.1 EU/mg), LL-37 gives you crisp, reproducible data every time.
⚠️ Important Disclaimer
For Research Use Only. Not for human consumption or therapeutic treatment.
LL-37
KEY HIGHLIGHTS
Antimicrobial Activity
LL-37 rapidly disrupts bacterial membranes in vitro, making it ideal for quantifying antimicrobial potency.
Wound-Healing Modeling
Promotes keratinocyte and fibroblast migration in scratch assays, providing a clear readout of tissue-repair dynamics.
Immune-Signaling Insights
Activates Toll-like receptor pathways and cytokine release in macrophage cultures, supporting innate-immunity studies.
Biofilm Disruption
Penetrates and breaks down bacterial biofilms in static-culture models, enabling advanced infection-control research.
Anti-Inflammatory Modulation
Downregulates pro-inflammatory markers (e.g., IL-1β, TNF-α) in immune-cell assays, modeling resolution phases.
Ready-to-Use Format
Lyophilized powder—reconstitute in sterile water, store at 2–8 °C, and use within 7 days for consistent activity.
What Is LL-37 Peptide?
LL-37 is a naturally occurring, 37-amino-acid antimicrobial peptide (cathelicidin) that plays a key role in the body’s first line of defense. In research, LL-37 peptide is used to explore microbial killing, wound-closure mechanisms, and innate immune signaling, giving scientists a direct tool to study host-pathogen interactions and tissue repair.
Why Choose LL-37?
Unlike generic antimicrobial reagents, LL-37 combines broad-spectrum bacterial activity with tissue-repair support in one molecule. Its balanced profile—effective against planktonic bacteria and biofilms, yet supportive of keratinocyte/fibroblast migration—makes LL-37 the go-to peptide for integrated infection and healing research.
What Sets LL-37 Apart?
What sets Retatrutide apart from traditional single-pathway compounds like semaglutide is its ability to address multiple metabolic pathways at once, making it highly attractive for advanced obesity, diabetes, and longevity studies.
LL-37 FAQs
What is LL-37 peptide used for in research?
To study antimicrobial defense, biofilm disruption, wound closure, and innate-immune signaling.
How does LL-37 kill bacteria?
It binds and disrupts bacterial membranes, causing rapid cell lysis in culture assays.
Can LL-37 promote wound healing?
Yes—LL-37 accelerates keratinocyte and fibroblast migration in scratch-wound models.
What concentration is typical in vitro?
Researchers commonly use 1–10 µg/mL, adjusted per cell type and assay.
Does LL-37 affect inflammation?
LL-37 modulates immune signals, reducing IL-1β and TNF-α in macrophage assays.
How is LL-37 reconstituted?
Dissolve in Sterile Water for Injection, gently mix until clear, then use immediately or store at 2–8 °C.
What storage conditions are required?
Store powder at – 20 °C; use reconstituted solution within 7 days at 2–8 °C.
Can LL-37 disrupt biofilms?
Yes—it penetrates and disperses bacterial biofilms in static and flow-cell models.
Is LL-37 approved for clinical use?
No—strictly for research use only, not for therapeutic or veterinary applications.
Where can I buy LL-37 peptide?
Real Peptides offers ISO-certified, USA-made LL-37 (5 mg), ≥ 99% purity, and low endotoxin—available for research use only.