Tesofensine

KEY HIGHLIGHTS

Controlled Appetite-Suppression Models

Enables reproducible feeding-behavior assays in diet-induced obesity (DIO) rodent protocols.

Energy-Expenditure Profiling

Elevates UCP1 expression in brown-adipocyte cultures to measure thermogenic responses.

Neurotransmitter Dynamics

Modulates serotonin, norepinephrine, and dopamine reuptake endpoints in brain-slice or cell assays.

Oral Dosing Convenience

Uniform 500 µg capsules simplify gavage or dietary-mix studies—no weighing errors.

Extended Shelf Life

Ambient-stable formulation retains full activity for up to 18 months, easing inventory management.

Minimal Excipients

Contains only microcrystalline cellulose, keeping assay backgrounds clean and data clear.

What Is Tesofensine?

Tesofensine is a synthetic peptide designed to block the reuptake of three key neurotransmitters—serotonin, norepinephrine, and dopamine. In research settings, Tesofensine capsules are used to investigate how these combined effects influence feeding behavior, energy balance, and metabolic pathways in both in vitro and in vivo models.

Why Choose Tesofensine Capsules?

Researchers choose Tesofensine capsules for their ease of use and consistent oral dosing. Capsules remove the variability of powder measurements and mimic human oral-delivery routes, making them ideal for long-term appetite and metabolism studies. Plus, the precise 500 µg dosage ensures each experiment starts with the same exact amount of active peptide.

What Sets Tesofensine Apart?

Unlike single-pathway compounds, Tesofensine’s triple-reuptake inhibition offers a unique research tool to probe the combined roles of serotonin, norepinephrine, and dopamine in metabolic regulation. Its capsule format and high purity make it a standout choice for labs requiring reproducible, translational oral-dosing protocols.

Tesofensine FAQs

What is Tesofensine used for in research?

To model appetite suppression, energy expenditure, and neurotransmitter activity in preclinical studies.

How much Tesofensine is in each capsule?

Each capsule delivers 500 µg of Tesofensine.

Can I open the Tesofensine capsules for in vitro assays?

Yes—contents dissolve quickly in aqueous buffers or culture medium for precise dosing.

What animal doses are typical?

Common rodent protocols use 0.1–1 mg/kg via oral gavage or dietary mix.

What in vitro concentration is recommended?

Cell-culture assays often range between 100–500 nM, adjusted per cell type.

How should Tesofensine capsules be stored?

Store at room temperature (15–25 °C) in a dry area; shelf life is 18 months.

Why use capsules instead of powder?

Capsules ensure uniform dosing, eliminate weighing errors, and reduce contamination risk.

Are there any fillers in Tesofensine capsules?

Only pharmaceutical-grade microcrystalline cellulose, minimizing background noise.

Is Tesofensine endotoxin-tested?

The active peptide is HPLC-verified to ≥ 99% purity; for cell-culture use, solutions can be filtered if needed.

Where can I buy Tesofensine 500 µg capsules?

Real Peptides offers Tesofensine 500 µg (100 ct), USA-made, ≥ 99% purity—research use only.

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