KPV
KPV peptide (Lys-Pro-Val) is a naturally derived tripeptide used to study anti-inflammatory and tissue-repair pathways in preclinical models. In macrophage, keratinocyte, and ex vivo skin assays, KPV modulates cytokine release, accelerates wound closure, and supports barrier recovery. Each 10 mg vial is USA-made, HPLC-verified to ≥ 99% purity, endotoxin-screened (< 0.1 EU/mg), and ideal for your in vitro and in vivo research.
⚠️ Important Disclaimer
For Research Use Only. Not for human consumption or therapeutic treatment.
Pairs well with
Peptides are not ready to use. Must purchase BAC water for reconstitution.
KPV
KPV
KEY BENEFITS
Cytokine Modulation
KPV peptide downregulates IL-1β and TNF-α in macrophage assays, modeling key kpv peptide benefits in inflammation-resolution research.
Accelerated Wound Closure
In scratch assays, KPV enhances keratinocyte migration—reducing gap closure time by up to 50%.
Barrier-Function Support
Ex vivo skin explants treated with KPV show faster transepidermal water-loss recovery, aiding barrier-integrity studies.
Antioxidant Enzyme Induction
KPV boosts superoxide dismutase (SOD) and catalase in oxidative-stress models, extending cellular resilience.
Neuroinflammation Modeling
In neural-glial co-cultures, KPV attenuates microglial activation, offering a tool for CNS inflammation research.
Lab-Friendly Prep & Storage
Reconstitute KPV in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC). Store lyophilized at –20 °C; keep reconstituted solution at 2–8 °C for up to 7 days to maintain ≥ 98% integrity.
What Is KPV Peptide?
KPV peptide (Lys-Pro-Val) is a tripeptide fragment derived from α-melanocyte-stimulating hormone, prized in research for its cell-level anti-inflammatory and tissue-repair actions. In controlled lab settings—covering macrophage, keratinocyte, endothelial, and neural-glial models—KPV probes how cytokines, cell migration, and barrier function interact during inflammation and healing.
Why Choose KPV Peptide?
Researchers choose KPV peptides when they need a high-precision tool to model inflammation resolution and barrier restoration. Its rapid cellular uptake and clear dose–response make it ideal for scratch assays, cytokine profiling, and barrier studies. Manufactured under ISO-certified conditions and verified to ≥ 99% purity—each batch is endotoxin-screened (< 0.1 EU/mg)—ensuring consistent, reproducible data for KPV peptide research.
What Sets KPV Peptide Apart?
Unlike broad-spectrum anti-inflammatory agents, KPV peptide acts through a specific Lys-Pro-Val sequence to simultaneously modulate immune and epithelial cell functions. Its dual capacity to induce antioxidant enzymes, suppress pro-inflammatory mediators, and accelerate barrier repair in ex vivo explants makes KPV a uniquely versatile reagent for integrated skin, neural, and vascular inflammation research.
KPV FAQs
What is KPV peptide?
A tripeptide (Lys-Pro-Val) used to study anti-inflammatory and wound-healing pathways in preclinical models.
What are the key kpv peptide benefits?
Benefits include cytokine modulation (↓ IL-1β, TNF-α), accelerated cell migration, and improved barrier recovery.
How do researchers use KPV peptides?
Commonly in scratch assays, macrophage-cytokine tests, ex vivo skin explants, and neural-glial inflammation models.
What is the typical kpv peptide dosage?
In vitro studies range from 100 nM to 10 µM; in vivo rodent assays often use 0.1–1 mg/kg.
Does KPV peptide have side effects?
As a research reagent, KPV shows no systemic side effects but must be handled under lab-safety protocols.
How is KPV peptide reconstituted?
Dissolve in SWFI or BAC water according to your SOP, then vortex gently until fully solubilized.
What storage conditions are required?
Store lyophilized at –20 °C; keep reconstituted solution at 2–8 °C and use within 7 days.
Can KPV peptides be combined with other peptides?
Yes—often co-studied with BPC-157, GHK-Cu, or TB-4 to explore synergistic tissue-repair and anti-inflammation effects.
Are KPV peptides approved for therapeutic use?
No—KPV is strictly for research use only and not approved for human or veterinary application.
Where can I buy KPV peptide online?
Real Peptides offers USA-manufactured, ISO-certified KPV peptide at ≥ 99% purity and low endotoxin—available for research use only.