In Stock, Ready to Ship!
$300.00 — or subscribe and save 20%
99% Pure | USA Made | Multi DoseFOXO4-DRI is a synthetic peptide designed to disrupt the interaction between FOXO4 and p53, prompting targeted clearance of senescent cells in cell culture and animal models. Researchers use FOXO4-DRI to study cellular aging, senescence-associated secretory phenotype (SASP) modulation, and longevity signaling. Each 10 mg vial is USA-manufactured and tested to ≥99% purity, with endotoxin <0.1 EU/mg—ideal for your peptide-driven aging research.
Peptides are not ready to use. Must purchase BAC water for reconstitution.
FOXO4-DRI is a “designed-retro-inverso” peptide that mimics the FOXO4 protein’s binding region in reverse sequence and D-amino-acid form. This design enables it to enter cells and competitively displace FOXO4 from p53, selectively driving senescent cells into programmed cell death. It’s used in preclinical aging and tissue-regeneration models to study the impact of senescent-cell removal on tissue function.
Researchers choose FOXO4-DRI for its unmatched ability to target senescent cells without harming normal proliferating cells. Its retro-inverso design delivers enhanced stability in culture and in vivo, while rigorous purity testing ensures reproducible results. FOXO4-DRI provides a precise, scalable approach for labs exploring anti-aging, regenerative medicine, and cell-stress response protocols.
Unlike broad-spectrum senolytic compounds, FOXO4-DRI offers molecular specificity by disrupting a single protein–protein interaction (FOXO4:p53) to induce apoptosis only in senescent cells. Its D-amino-acid retro-inverso configuration grants exceptional resistance to proteolytic degradation, ensuring consistent activity throughout your experiments. FOXO4-DRI is the go-to peptide for clean, targeted senescence research.
Don't hestitate to contact us
End of Content.
