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Circadian Peptides · Inflammatory Pathway Peptides

Pinealon

Q: What is Pinealon peptide used for in research?

To study neuroprotection, mitochondrial resilience, and cognitive-aging pathways in cell and animal models.

Q: How does Pinealon protect neurons?

By preserving mitochondrial membrane potential and reducing ROS under oxidative stress.

Q: What concentration is typical in vitro?

Commonly 1–10 µM, adjusted per neuron or glial cell assay.

Q: Can Pinealon improve mitochondrial function?

Yes—treated cultures show increased ATP production and stabilized membrane potential.

Q: Does Pinealon affect inflammation in the brain?

It downregulates IL-1β and TNF-α in microglial assays, modeling anti-inflammatory effects.

Q: How do I prepare Pinealon peptide?

Reconstitute in Sterile Water for Injection, mix gently, then use immediately or store at 2–8 °C.

Q: What storage conditions are required?

Store powder at –20 °C; use reconstituted solution within 7 days at 2–8 °C.

Q: Is Pinealon approved for clinical use?

No—strictly for research use only, not for therapeutic or veterinary applications.

Q: Can Pinealon be combined with other neuropeptides?

Yes—often paired with BDNF mimetics or antioxidant peptides for synergistic neuroprotection studies.

Q: Where can I buy Pinealon peptide?

Real Peptides offers Pinealon (10 mg), ≥ 99% purity, and low endotoxin—available for research use only.

~~$50.00~~$25.00Save 50%

Finished in the USA

99% Pure | Multi Dose Pinealon is a small, brain-derived peptide that’s become a go-to for labs studying neuroprotection, mitochondrial health, and cognitive-aging pathways. Each 10 mg vial delivers a ready-to-use peptide that helps preserve neuronal function under stress, supports energy-metabolism assays, and models age-related decline—no extra factors needed.

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Pinealon · 10mg

$25.00$50.00

Recommended with this order

Frequently paired with this compound by other researchers.

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Bacteriostatic Reconstitution Water (BAC)~~$15.00~~$7.50

10ml

For Research Use Only. Not for human consumption or therapeutic treatment.

AboutLab reportSpecificationsQuestions

Finished in the USA

99% Pure | Multi Dose

Pinealon is a small, brain-derived peptide that’s become a go-to for labs studying neuroprotection, mitochondrial health, and cognitive-aging pathways. Each 10 mg vial delivers a ready-to-use peptide that helps preserve neuronal function under stress, supports energy-metabolism assays, and models age-related decline—no extra factors needed. HPLC-verified at ≥ 99% purity, and endotoxin-screened (< 0.1 EU/mg), Pinealon brings consistent, easy-to-interpret results to your neuroscience protocols.

What Is Pinealon Peptide?

Pinealon is a tripeptide derived from the pineal gland’s protein fragments. In research, it’s used to explore neuronal survival, mitochondrial health, and cognitive-aging mechanisms under controlled laboratory conditions.

Why Choose Pinealon?

Choose Pinealon when you need a straightforward, powerful peptide to model brain-aging and neuroprotection. Its proven ability to shield neurons from stress and boost mitochondrial function makes it ideal for labs investigating dementia, oxidative damage, and age-related cognitive decline. Manufactured and verified to ≥ 99% purity, Pinealon delivers reproducible, high-quality data every time.

What Sets Pinealon Apart?

Unlike generic small peptides, Pinealon combines neuroprotective and mitochondrial-support actions in one molecule. Its tripeptide structure allows rapid cell uptake, acting without off-target effects. That makes Pinealon uniquely suited for high-throughput and long-term studies of brain health and aging.

Research observations

Neuroprotective Support

Protects neuron-like cells against oxidative and excitotoxic stress, preserving cell viability in culture.

Mitochondrial Function

Enhances mitochondrial membrane potential and ATP production in neuronal assays, modeling energy resilience.

Cognitive-Aging Models

Mitigates age-related markers (e.g., ROS, lipid peroxidation) in senescence-induced neuron cultures

Synaptic Health

Supports synaptophysin and PSD-95 expression in hippocampal slice preparations, aiding memory-pathway studies.

Anti-Inflammatory Action

Downregulates pro-inflammatory cytokines (IL-1β, TNF-α) in microglial assays, modeling neuroinflammation resolution.

Ready-to-Use Format

Lyophilized powder—reconstitute in sterile water, store at 2–8 °C, and use within 7 days for consistent activity.

Tested 20-Aug-2026

Kovera · 2 reports · 99.726% pure

1 earlier

CompoundPinealon

Research areaCircadian Peptides, Inflammatory Pathway Peptides, Mood Pathway Peptides, Popular Peptides, Cognitive & Neurological Research, Focus & Cognition Research, Mitochondrial Peptides, CNS & Neuropeptide Research

FormatLyophilised powder, sealed glass vial

Sizes10mg

Reconstituted shelf life30 days at 2–8°C

Independent laboratoryFreedom Diagnostics and Kovera

Lab reports on file2 reports

Ships fromSaint Petersburg, FL and California

DispatchWithin 24 hours

To study neuroprotection, mitochondrial resilience, and cognitive-aging pathways in cell and animal models.

By preserving mitochondrial membrane potential and reducing ROS under oxidative stress.

Commonly 1–10 µM, adjusted per neuron or glial cell assay.

Yes—treated cultures show increased ATP production and stabilized membrane potential.

It downregulates IL-1β and TNF-α in microglial assays, modeling anti-inflammatory effects.