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For Research Use Only. Not for human consumption or therapeutic treatment. 99% Pure | USA Made | Multi DoseSelank Amidate is a modified heptapeptide analog of the natural immunomodulator tuftsin, designed for preclinical studies of anxiolytic effects, cognitive enhancement, and neuroprotective signaling. In rodent behavioral assays and neuronal-culture models, Selank Amidate modulates GABAergic pathways, boosts BDNF expression, and supports stress-resilience research. Each 10 mg vial is USA-manufactured, HPLC-verified to ≥ 99% purity, endotoxin-screened (< 0.1 EU/mg), and formulated exclusively for laboratory investigation.
Peptides are not ready to use. Must purchase BAC water for reconstitution.
Selank Amidate modulates GABA-A receptor subunits in rodent models, providing a tool for anxiety-related behavior research.
In hippocampal neuron assays, Selank upregulates BDNF and CREB phosphorylation—key markers of learning and memory.
Behavioral stress-test protocols (e.g., elevated-plus maze) show reduced anxiety indices following Selank Amidate administration.
Selank peptide reduces glutamate-induced excitotoxicity in cortical neuron cultures, modeling protective mechanisms.
In microglial assays, Selank Amidate downregulates pro-inflammatory cytokines (IL-1β, TNF-α), linking immune modulation to neural health.
Reconstitute in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC). Store lyophilized at – 20 °C; keep reconstituted peptide at 2–8 °C and use within 7 days to maintain ≥ 98% integrity.
Selank Amidate is a chemically stabilized analog of the endogenous immunoregulatory peptide Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro). By amidating its C-terminus, it gains enhanced resistance to enzymatic degradation, making it ideal for in vitro and in vivo models of anxiety modulation, cognitive function, and neuroinflammation. Researchers leverage Selank Amidate to dissect peptide-driven pathways in brain regions governing stress, memory, and mood.
Researchers select Selank Amidate for its dual action on neurochemical and immune pathways. Its proven ability to reduce anxiety-like behaviors, boost neurotrophic factors (BDNF), and modulate cytokine profiles provides a versatile platform for preclinical neuropsychiatric and neurodegenerative research. Manufactured under ISO-certified conditions and verified to ≥ 99% purity by HPLC—with endotoxin < 0.1 EU/mg—Selank Amidate delivers consistent, reproducible outcomes for high-impact cognitive and anxiolytic studies.
Unlike unmodified peptides, Selank Amidate’s C-terminal amidation confers enhanced metabolic stability and extended half-life in biological models. It uniquely combines anxiolytic and cognitive-enhancing effects with anti-inflammatory properties, allowing simultaneous investigation of mood-behavior and neuroimmune interactions. Its robust performance in both behavioral and cellular assays makes Selank Amidate the go-to peptide for neuro-behavioral, stress, and cognitive research.
A stabilized analog of the heptapeptide Selank, used to study anxiety modulation, cognitive function, and neuroimmune signaling in research models.
By modulating GABA-A receptor activity and neurotrophic signaling pathways, leading to lower anxiety-like behavior in maze and stress assays.
Yes—Selank Amidate upregulates BDNF and CREB phosphorylation in hippocampal cultures, modeling molecular mechanisms of learning and memory.
Commonly in anxiety-behavior tests (elevated-plus maze), cognitive-task assays, and neuroinflammation models using microglial cultures.
In vitro work often uses 100 nM–10 µM; in rodent in vivo assays, doses range 0.1–1 mg/kg, per protocol.
Dissolve in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC) per your SOP and mix gently until clear.
Store lyophilized at – 20 °C; keep reconstituted peptide at 2–8 °C and use within 7 days to maintain ≥ 98% integrity.
In microglial assays, Selank reduces IL-1β and TNF-α expression, modeling neuroimmune crosstalk in research.
No—Selank Amidate is strictly for research use only and not approved for human or veterinary application.
Real Peptides offers ISO-certified, USA-manufactured Selank Amidate (10 mg) at ≥ 99% purity and low endotoxin—available for research use only.
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