In Stock, Ready to Ship!
$550.00
99% Pure | USA Finished | Multi-Use Format Neuropeptide Research Bundle — a three-reagent set of peptides appearing in published CNS and neurosignaling literature. Supplied pre-solubilized in a multi-use dispenser, eliminating reconstitution variability between experiments. Each lot is USA-manufactured, HPLC-verified to ≥99% purity, and endotoxin-screened (<0.1 EU/mg). COAs available per lot. For Research Use Only. Not for human or veterinary use.
Product Individual Price MOTS-c Liquid Spray $200 Semax Liquid Spray $200 Selank Liquid Spray $200 Total if Bought Individually $600 Bundle Price Best Value $600$550You Save $50
In Stock, Ready to Ship!
MOTS-c activates AMP-activated protein kinase (AMPK) in myocyte and hepatocyte cultures, modeling enhanced glucose uptake and lipid oxidation.
MOTS-c is referenced in published rodent-model studies examining metabolic signalling pathways. Supplied as a research reagent; no physiological effect is claimed or implied.
Published rodent-model literature reports endogenous MOTS-c expression in skeletal muscle. Supplied as a research reagent; no physiological effect is claimed or implied.
MOTS-c is cited in published in vitro and preclinical literature examining sphingolipid and monoacylglycerol pathway activity. Supplied as a research reagent; no physiological effect is claimed or implied.
MOTS-c is referenced in fibroblast assay literature examining expression of PGC-1α and Nrf2. Supplied as a research reagent; no physiological effect is claimed or implied.
Pre-formulated liquid spray — no reconstitution required, no injection. Store at 2–8°C, protect from light. Maintains ≥98% integrity throughout shelf life.
MOTS-c (Mitochondrial Open-Reading-Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within the mitochondrial genome itself — one of the very few peptides known to originate there rather than in nuclear DNA. First characterized at the USC Leonard Davis School of Gerontology in 2015, MOTS-c acts as a mitochondrial hormone, signaling through AMPK and related metabolic pathways to regulate glucose and lipid homeostasis. Real Peptides is the first supplier to offer MOTS-c in liquid spray format — expanding research access beyond traditional injectable-only protocols.
Researchers study MOTS-c in the context of mitochondrial-to-nuclear signalling and cellular metabolism. Manufactured in USA facilities and verified ≥99% pure by HPLC with endotoxin <0.1 EU/mg. Supplied for laboratory research use only.
MOTS-c is the only widely-studied peptide encoded directly by mitochondrial DNA rather than the nuclear genome. That makes it a uniquely direct biological messenger between cellular energy status and nuclear gene programs — essentially, a molecular signal that bridges the cell’s power plant and its command center. It’s commonly studied alongside broader mitochondrial and metabolic peptides in energy-metabolism research.
MOTS-c is studied in research contexts including mitochondrial signalling, AMPK pathway activity, and gene expression. It is a 16-amino-acid mitochondrial-derived peptide supplied by Real Peptides for laboratory research use only — not for human consumption or therapeutic use.
Published literature describes MOTS-c interaction with the folate cycle and de novo purine biosynthesis, leading to AICAR accumulation and AMP-activated protein kinase pathway activity, with downstream reports of PGC-1α and Nrf2 gene expression. Supplied as a research reagent; no physiological effect is claimed or implied.
Published literature covering MOTS-c includes AMPK pathway activity in myocyte cultures, cellular metabolic signalling in preclinical models, sphingolipid and monoacylglycerol pathway activity, and expression of PGC-1α and Nrf2. These describe published findings only. Real Peptides supplies MOTS-c strictly for laboratory research use — not for human consumption or therapeutic use.
Published studies report endogenous MOTS-c expression in skeletal muscle tissue. These describe published findings in research models only. Real Peptides supplies MOTS-c strictly for laboratory research use — not for human consumption or therapeutic use.
MOTS-c is supplied pre-solubilised in a multi-use dispenser, removing the reconstitution step between experiments. Supplied for laboratory research use only — not for human consumption or therapeutic use.
No. MOTS-c is an investigational research compound and is not FDA-approved in the United States or any other country. Real Peptides supplies MOTS-c liquid spray strictly for laboratory research use only — not for human consumption or therapeutic use.
MOTS-c appears in published literature across mitochondrial signalling, gene expression, and cellular metabolism research. Real Peptides supplies MOTS-c strictly for laboratory research use — not for human consumption or therapeutic use.
MOTS-c is unique because it is encoded within mitochondrial DNA rather than the nuclear genome — one of the only known peptides with this origin. This makes it a direct molecular messenger between the mitochondria and the nucleus, giving researchers a precise tool for studying mitochondrial-to-nuclear signaling that other peptides cannot replicate. Compare with our cognitive peptides or browse the full mitochondrial collection.
Each Real Peptides MOTS-c liquid spray bottle contains 10mg of peptide across multiple metered doses. The delivery system provides approximately 200mcg per 2-spray actuation, calibrated for consistent research dosing.
Store MOTS-c liquid spray at 2–8°C (refrigerated), protected from light. Do not freeze. When stored correctly, the formulation maintains ≥98% integrity throughout its shelf life.
Real Peptides is the only supplier offering MOTS-c liquid spray — USA-manufactured, HPLC-verified at ≥99% purity, in a 10mg multi-dose format. Presale pricing is $200 ($100 off the $300 MSRP), with orders shipping May 3. Also see the injectable MOTS-c peptide if your protocol requires that format, or browse mitochondrial research peptides for related compounds.
Don't hestitate to contact us
