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Selank nasal spray is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) studied in research for anxiolytic, nootropic, and immune-modulatory effects. Each 10mg bottle delivers 200mcg per 2-spray actuation, is USA-manufactured, HPLC-verified to ≥99% purity, endotoxin-screened (<0.1 EU/mg), and formulated for laboratory research.
SHIPS: Week Of May 3rd
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Peptides are not ready to use. Must purchase BAC water for reconstitution.
In rodent anxiety assays, Selank produces anxiolytic effects comparable to benzodiazepines without the sedation, dependence, or withdrawal markers characteristic of that drug class.
Selank rapidly elevates brain-derived neurotrophic factor (BDNF) expression in the hippocampus, making it a research tool for neuroplasticity and memory studies.
Selank allosterically modulates GABA-A receptor activity in neuronal assays — binding without directly agonizing the receptor, which distinguishes it from classical anxiolytics.
Selank influences monoamine metabolism in preclinical models, making it relevant for mood, attention, and cognitive research.
As a tuftsin analog, Selank modulates IL-6 expression and Th1/Th2 cytokine balance, bridging neuroscience and immunology research.
Pre-formulated nasal spray — no reconstitution required. Store at 2–8°C, protect from light. Maintains ≥98% integrity throughout shelf life.
Selank is a synthetic seven-amino-acid peptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from tuftsin, a natural fragment of human immunoglobulin G. Developed at the Russian Academy of Sciences, Selank is studied in preclinical and clinical research for anxiolytic, nootropic, and immunomodulatory activity. It acts on GABAergic, serotonergic, noradrenergic, and enkephalin pathways, giving researchers a multi-system tool for studying anxiety, cognition, and neuroimmune crosstalk — all without the sedation profile of benzodiazepine-class compounds.
Researchers choose Selank nasal spray when they need a precise tool for studying anxiety pathways, cognitive resilience, and neuroimmune modulation. The intranasal format delivers Selank through the olfactory and trigeminal pathways — a direct route to the central nervous system that bypasses first-pass metabolism entirely. Manufactured in USA facilities and HPLC-verified at ≥99% purity with endotoxin <0.1 EU/mg, Real Peptides Selank delivers reproducible, high-fidelity data across behavioral, electrophysiological, and neurochemical research models.
Unlike benzodiazepine-class compounds, Selank engages GABA pathways through allosteric modulation rather than direct receptor agonism — meaning it can produce anxiolytic-like effects in research models without the hallmarks of sedation, dependence, or withdrawal. Its dual identity as both an anxiolytic and an immunomodulator makes Selank uniquely versatile: one peptide, studied across anxiety, cognition, and immune research. That’s why researchers frequently pair Selank with Semax nasal spray for combined nootropic-anxiolytic research designs.
Selank nasal spray is used in research to study anxiety pathways, cognitive function, neurotransmitter modulation, and immune signaling. It is a synthetic heptapeptide derived from tuftsin, originally developed in Russia and now available from Real Peptides as a 10mg multi-dose nasal spray for laboratory research.
Selank works by allosterically modulating GABA-A receptors, elevating BDNF expression in the hippocampus, inhibiting enkephalin-degrading enzymes, and influencing serotonin, dopamine, and noradrenaline metabolism. Research shows these effects produce anxiolytic and nootropic activity in preclinical models without engaging the sedation pathways typical of benzodiazepines.
Research has documented five primary Selank benefits: (1) anxiolytic activity comparable to benzodiazepines without sedation, (2) elevated BDNF expression supporting neuroplasticity, (3) GABAergic modulation without direct receptor agonism, (4) monoamine system regulation affecting mood and cognition, and (5) immunomodulatory activity through IL-6 and Th1/Th2 cytokine pathways.
In research settings, Selank nasal spray reaches the central nervous system within minutes of administration via olfactory pathway absorption. Published clinical research reports anxiolytic effects measurable within the first days of a protocol, with peak effects typically observed by day 14 of consistent administration.
Published research reports that Selank has a favorable safety profile with no documented addiction, withdrawal, or sedation. In research settings, the most commonly noted effect is mild transient nasal irritation from the intranasal route itself rather than the peptide. Real Peptides Selank is supplied for laboratory research only and is not for human consumption.
No. Selank is not FDA-approved in the United States. It is approved in Russia for clinical use in generalized anxiety disorder and neurasthenia under the trade name Selank. Real Peptides supplies Selank nasal spray strictly for laboratory research use.
Selank and Semax are both Russian-developed heptapeptides with a shared Pro-Gly-Pro C-terminal stability extension. Selank is derived from tuftsin and is primarily studied for anxiolytic and immunomodulatory activity. Semax is derived from ACTH(4-10) and is primarily studied for nootropic and neuroprotective activity. Many research protocols pair the two.
Yes. Selank is frequently co-studied with Semax (shared pharmacological lineage, complementary research targets) and with broader cognitive peptide panels. Its clean side-effect profile in research models makes it a common baseline peptide in combination study designs.
Each Real Peptides Selank bottle contains 10mg of peptide across multiple metered doses. The delivery system provides approximately 200mcg per 2-spray actuation, calibrated for consistent research dosing.
Store Selank nasal spray at 2–8°C (refrigerated), protected from light. Do not freeze. When stored correctly, the formulation maintains ≥98% integrity throughout its shelf life.
Real Peptides sells Selank nasal spray in a 10mg multi-dose format, USA-manufactured and HPLC-verified at ≥99% purity. Presale pricing is $200 ($100 off the $300 MSRP), with orders shipping May 3. See our full peptide catalog or browse popular peptides for related research compounds.
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