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Myogenic Peptides · Performance & Recovery Research
Semax Amidate
$60.00$30.00Save 50%
99% Pure | Multi Dose | Finished in the USA
Semax Amidate is a stabilized heptapeptide analog of the endogenous ACTH fragment, designed for preclinical studies of cognitive function, neuroprotection, and stress resilience. In rodent learning-and-memory tasks and neuronal-culture models, Semax modulates BDNF expression, supports antioxidant defenses, and regulates stress-axis markers.
For Research Use Only. Not for human consumption or therapeutic treatment.
99% Pure | Multi Dose | Finished in the USA
Semax Amidate is a stabilized heptapeptide analog of the endogenous ACTH fragment, designed for preclinical studies of cognitive function, neuroprotection, and stress resilience. In rodent learning-and-memory tasks and neuronal-culture models, Semax modulates BDNF expression, supports antioxidant defenses, and regulates stress-axis markers. Each 10 mg vial is HPLC-verified to ≥ 99% purity, endotoxin-screened (< 0.1 EU/mg), and tailored for laboratory research.
What Is Semax Amidate?
Semax Amidate is a chemically modified version of the ACTH(4–10) fragment, engineered with C-terminal amidation for enhanced stability. As a cognitive and neuroprotective research peptide, it interacts with neurotrophic and stress-response pathways—making it ideal for exploring BDNF-mediated plasticity, oxidative-stress defenses, and behavioral-stress modulation in vitro and in vivo models.
Why Choose Semax Amidate?
Researchers select Semax Amidate for its dual action on cognitive-enhancement and neuro-resilience. Its proven ability to upregulate BDNF, stabilize synaptic markers, and modulate stress hormones provides a versatile platform for neurodegenerative- and stress-related research. Manufactured and verified to ≥ 99% purity by HPLC—with endotoxin < 0.1 EU/mg—Semax Amidate delivers consistent, reproducible data for advanced neuroscience studies.
What Sets Semax Amidate Apart?
Unlike unmodified peptides, Semax Amidate’s C-terminal amidation and sequence tweaks confer extended enzymatic resistance and improved blood-brain-barrier penetration in rodent models. It uniquely combines cognitive-boosting and neuroprotective effects without affecting systemic hormone levels. This makes Semax Amidate the go-to peptide for dissecting synaptic plasticity, stress resilience, and cell-survival mechanisms in high-resolution preclinical assays.
Research observations
01
Cognitive-Enhancement Modeling
Semax Amidate boosts BDNF and CREB phosphorylation in hippocampal cultures—modeling learning-and-memory pathways.
Rodent elevated-plus-maze and forced-swim tests show Semax reduces stress-hormone markers (corticosterone), modeling resilience.
04
Synaptic Plasticity Support
Improves synaptophysin and PSD-95 expression in cortical neuron cultures, offering a tool for synaptic-function studies.
05
Anti-Inflammatory Modulation
Semax downregulates pro-inflammatory cytokines (IL-6, TNF-α) in microglial cultures, linking immune and neural health.
06
Lab-Friendly Prep & Storage
Reconstitute in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC). Store lyophilized at – 20 °C; keep reconstituted solution at 2–8 °C for up to 7 days to maintain ≥ 98% integrity.
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