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Myogenic Peptides · Gastrointestinal Peptides
KPV
$85.00$42.50Save 50%
Finished in the USA
99% Pure | Multi Dose KPV peptide (Lys-Pro-Val) is a naturally derived tripeptide used to study anti-inflammatory and tissue-repair pathways in preclinical models. In macrophage, keratinocyte, and ex vivo skin assays, KPV modulates cytokine release, accelerates wound closure, and supports barrier recovery.
For Research Use Only. Not for human consumption or therapeutic treatment.
Finished in the USA
99% Pure | Multi Dose
KPV peptide (Lys-Pro-Val) is a naturally derived tripeptide used to study anti-inflammatory and tissue-repair pathways in preclinical models. In macrophage, keratinocyte, and ex vivo skin assays, KPV modulates cytokine release, accelerates wound closure, and supports barrier recovery. Each 10 mg vial is HPLC-verified to ≥ 99% purity, endotoxin-screened (< 0.1 EU/mg), and ideal for your in vitro and in vivo research.
What Is KPV Peptide?
KPV peptide (Lys-Pro-Val) is a tripeptide fragment derived from α-melanocyte-stimulating hormone, prized in research for its cell-level anti-inflammatory and tissue-repair actions. In controlled lab settings—covering macrophage, keratinocyte, endothelial, and neural-glial models—KPV probes how cytokines, cell migration, and barrier function interact during inflammation and healing.
Why Choose KPV Peptide?
Researchers choose KPV peptides when they need a high-precision tool to model inflammation resolution and barrier restoration. Its rapid cellular uptake and clear dose–response make it ideal for scratch assays, cytokine profiling, and barrier studies. Manufactured and verified to ≥ 99% purity—each batch is endotoxin-screened (< 0.1 EU/mg)—ensuring consistent, reproducible data for KPV peptide research.
What Sets KPV Peptide Apart?
Unlike broad-spectrum anti-inflammatory agents, KPV peptide acts through a specific Lys-Pro-Val sequence to simultaneously modulate immune and epithelial cell functions. Its dual capacity to induce antioxidant enzymes, suppress pro-inflammatory mediators, and accelerate barrier repair in ex vivo explants makes KPV a uniquely versatile reagent for integrated skin, neural, and vascular inflammation research.
Research observations
01
Cytokine Modulation
KPV peptide downregulates IL-1β and TNF-α in macrophage assays, modeling key kpv peptide findings in inflammation-resolution research.
02
Accelerated Wound Closure
In scratch assays, KPV enhances keratinocyte migration—reducing gap closure time by up to 50%.
03
Barrier-Function Support
Ex vivo skin explants treated with KPV show faster transepidermal water-loss recovery, aiding barrier-integrity studies.
04
Antioxidant Enzyme Induction
KPV boosts superoxide dismutase (SOD) and catalase in oxidative-stress models, extending cellular resilience.
05
Neuroinflammation Modeling
In neural-glial co-cultures, KPV attenuates microglial activation, offering a tool for CNS inflammation research.
06
Lab-Friendly Prep & Storage
Reconstitute KPV in Sterile Water for Injection (SWFI) or Bacteriostatic Water (BAC). Store lyophilized at –20 °C; keep reconstituted solution at 2–8 °C for up to 7 days to maintain ≥ 98% integrity.
Tested 22-Oct-2025
2 reports
1 earlier
CompoundKPV
Research areaMyogenic Peptides, Gastrointestinal Peptides, Inflammatory Pathway Peptides, Popular Peptides, Gastrointestinal & Epithelial Research
FormatLyophilised powder, sealed glass vial
Sizes10mg
Reconstituted shelf life30 days at 2–8°C
Independent laboratoryFreedom Diagnostics and Kovera
Lab reports on file2 reports
Ships fromSaint Petersburg, FL and California
DispatchWithin 24 hours
A tripeptide (Lys-Pro-Val) used to study anti-inflammatory and wound-healing pathways in preclinical models.
Documented findings include cytokine modulation (↓ IL-1β, TNF-α), accelerated cell migration, and improved barrier recovery.
Commonly in scratch assays, macrophage-cytokine tests, ex vivo skin explants, and neural-glial inflammation models.
In vitro studies range from 100 nM to 10 µM; in vivo rodent assays often use 0.1–1 mg/kg.
KPV is supplied as a laboratory research reagent and must be handled under standard lab-safety protocols. It is not for human or veterinary use.
Yes—often co-studied with BPC-157, GHK-Cu, or TB-4 to explore synergistic tissue-repair and anti-inflammation effects.
No—KPV is strictly for research use only and not approved for human or veterinary application.
Real Peptides offers KPV peptide at ≥ 99% purity and low endotoxin—available for research use only.
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