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Performance & Recovery Research · Gastrointestinal Peptides
TB-500 (Thymosin Beta-4)
$100.00$60.00Save 40%
99% Pure | USA Finish | Multi Dose | Finished in the USA
TB500 (Thymosin Beta-4) is a synthetic 43-amino-acid peptide fragment used in preclinical models to explore tissue repair, cell migration, and inflammation resolution. In cell-culture wound-closure assays and rodent injury models, TB-500 accelerates fibroblast migration, modulates cytokine profiles, and supports angiogenic signaling.
For Research Use Only. Not for human consumption or therapeutic treatment.
99% Pure | USA Finish | Multi Dose | Finished in the USA
TB500 (Thymosin Beta-4) is a synthetic 43-amino-acid peptide fragment used in preclinical models to explore tissue repair, cell migration, and inflammation resolution. In cell-culture wound-closure assays and rodent injury models, TB-500 accelerates fibroblast migration, modulates cytokine profiles, and supports angiogenic signaling. Each 10 mg vial is HPLC-verified to ≥ 99% purity, endotoxin-screened (< 0.1 EU/mg), and formulated for laboratory research.
What is TB-500?
TB-500, also called TB500 or Thymosin Beta-4 peptide, is a synthetic fragment of the naturally occurring Thymosin β4 protein. It plays a key role in actin-binding, cell-migration, and repair signaling. In research contexts, TB-500 is applied to both in vitro and in vivo models to dissect pathways of tissue regeneration, angiogenesis, and inflammation resolution.
Why Choose TB-500 Peptide?
Researchers select TB-500 when they need a versatile tool for modeling wound healing, vascular growth and anti-inflammatory effects in controlled experiments. Its proven effect in accelerating cell migration and promoting capillary formation—coupled with ≥ 99% purity—ensures reproducible, high-quality data for regenerative-medicine and tissue-repair studies.
What Sets TB-500 Apart?
Unlike broader growth-factor agents, TB-500 peptide offers precise modulation of both cytoskeletal dynamics and angiogenic signaling via its actin-binding properties. Its dual action on cell migration and inflammation resolution, plus demonstrated stability in solution, makes TB-500 the go-to peptide for high-resolution studies of tissue repair and regenerative pathways.
Research observations
01
Accelerated Wound Closure
TB-500 peptide enhances fibroblast and keratinocyte migration in scratch assays—reducing gap closure time by up to 60%.
02
Angiogenesis Promotion
Upregulates VEGF and promotes capillary-tube formation in endothelial cultures, modeling blood-vessel growth.
03
VEGF-Mediated Angiogenesis
In endothelial cultures, TB-4 increases VEGF expression and capillary tube formation, enabling detailed microvascular growth studies.
04
Anti-Inflammatory Modulation
Anti-Inflammatory Modulation
05
Cell-Stress Resilience
Improves cell survival under oxidative or hypoxic stress by boosting mitochondrial function markers (ATP, membrane potential).
06
Extracellular Matrix Remodeling
Increases expression of matrix metalloproteinases (MMP-2, MMP-9) in fibroblasts, aiding studies of ECM turnover and tissue remodeling.
07
Lab-Grade Handling & Stability
TB-4 dissolves readily in SWFI or BAC water, remains stable lyophilized at –20 °C, and retains >99% integrity when stored reconstituted at 2–8 °C for up to 7 days.
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