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99% Pure | USA Made | Multi DoseIpamorelin is a pentapeptide GHS-R1a agonist used in preclinical models to stimulate pulsatile growth-hormone release without significant cortisol or prolactin elevation. Ideal for exploring anabolic signaling, IGF-1 activation, and pituitary feedback loops, each 10 mg vial is USA-manufactured, tested to ≥ 99% purity by HPLC, endotoxin-screened (< 0.1 EU/mg), and formulated exclusively for laboratory research.
Peptides are not ready to use. Must purchase BAC water for reconstitution.
Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) that specifically activates the growth-hormone secretagogue receptor (GHS-R1a), mimicking the natural ghrelin signal to provoke controlled GH release. Unlike broader-spectrum secretagogues, Ipamorelin triggers pulsatile spikes of growth hormone—allowing researchers to model the body’s own hormone rhythms in both cell cultures and animal studies. It is prized for its precise action on the pituitary gland without significant elevation of cortisol or prolactin, making it an ideal reagent for dissecting anabolic pathways, IGF-1 dynamics, and endocrine feedback loops under tightly defined laboratory conditions.
Researchers turn to Ipamorelin when they need a “clean” GH secretagogue that delivers robust growth-hormone surges without off-target hormone effects. Its high specificity for GHS-R1a ensures minimal interference with adrenal or lactotroph axes—so cortisol and prolactin remain stable while GH peaks. This profile makes Ipamorelin perfect for studies of lean-tissue anabolism, metabolic regulation, and receptor-feedback mechanisms. Manufactured under ISO-certified, cGMP-like conditions and verified to ≥ 99% purity by HPLC—with endotoxin < 0.1 EU/mg—each batch provides the consistency and reproducibility critical for hormone-axis and muscle-biology research.
Ipamorelin stands out from other GH-releasing peptides in three key ways:
It binds GHS-R1a with high affinity, triggering only growth-hormone release and avoiding unwanted cascades through cortisol or prolactin pathways.
With a half-life of roughly one hour, Ipamorelin offers researchers tight temporal control over GH pulses, enabling clear mapping of downstream IGF-1 responses and feedback regulation.
Unlike multi-axis secretagogues, Ipamorelin’s “single-axis” profile yields clean data on anabolic signaling without confounding hormone elevations—making it the gold standard for high-resolution endocrine and anabolic-pathway assays.
Together, these attributes make Ipamorelin the go-to research peptide for anyone studying the mechanics of GH release, lean-mass biology, or pituitary feedback with maximum specificity and minimal hormonal “noise.”
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