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Liquid Spray

MOTS-c Peptide Liquid Spray (25mg) for Laboratory Research

Q: Where can MOTS-c peptide be purchased for research use?

Real Peptides supplies MOTS-c directly from its own United States facilities in Florida and California, with in-stock orders leaving within 24 hours on business days. Each listing states the exact format and quantity supplied, and the certificate of analysis for the current lot is published on the lab results page so testing data can be reviewed before ordering.

Q: What is included in this MOTS-c for sale listing?

This page covers MOTS-c supplied as a 25mg liquid spray, prepared pre-solubilized so no reconstitution step is required in the laboratory. No other formats or quantities are included on this listing. Bacteriostatic water and related laboratory consumables are listed separately in the catalog. All materials are intended for in vitro and other non-human research applications only.

Q: How is the purity of the MOTS-c peptide verified?

Every batch is analyzed by an independent third-party laboratory rather than by in-house testing alone. Analysis typically covers identity and purity by HPLC and mass spectrometry, along with endotoxin screening. The certificate of analysis for the exact lot is published on the site, so the reported figures for the current lot can be checked before any purchase is made.

Q: Can the certificate of analysis be reviewed before buying?

Yes. Certificates are published in the lab results section and organized by compound and lot number, so documentation for the current MOTS-c lot is available before checkout rather than only on request afterward. The lot number printed on the bottle received can be matched against the published certificate for that batch.

Q: What is MOTS-c studied for in the laboratory?

MOTS-c is a mitochondrial-derived peptide encoded in the mitochondrial genome. Published preclinical literature examines its interaction with AMPK signaling and with metabolic and mitochondrial stress-response pathways in cell cultures and animal models. Real Peptides supplies the compound strictly as a research chemical; it is not a drug or supplement, and no clinical claims are made.

Q: Who is eligible to order MOTS-c from this site?

Orders are accepted from buyers who confirm they are 21 years of age or older and are purchasing strictly for laboratory research. No institutional affiliation or professional credential is required. All products are sold as research chemicals and are not drugs, dietary supplements, or cosmetics, and are not intended for human or animal use.

Q: How quickly do MOTS-c orders ship within the United States?

In-stock orders leave the Florida or California facility within 24 hours on business days, and tracking details are issued once the shipping label is created. Packages are packed discreetly to protect the contents in transit. Domestic transit time after dispatch depends on the carrier service selected during checkout.

Q: How should the MOTS-c liquid spray be handled on arrival?

On arrival, the liquid spray is generally refrigerated and kept away from light and heat; brief periods at room temperature during transit are normal for peptide shipments. Handling should follow standard laboratory practice for research chemicals, including keeping the bottle sealed when not in use and recording the lot number for reference against the published certificate.

MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the mitochondrial 12S rRNA gene, studied in cell and animal models for its role in AMPK-related signaling and mitochondrial stress-response pathways.

It is supplied here as a 25mg liquid spray, prepared pre-solubilized for laboratory handling. Every batch is analyzed by an independent laboratory, and the certificate for the current lot is published on the site's lab results page so it can be reviewed before purchase. Orders ship from facilities in Florida and California, typically within 24 hours on business days. The material is sold for laboratory research use only and is not a drug, dietary supplement, or cosmetic.

Current lot: 99.2% purity (HPLC) · Arrow Lab Solutions · tested 2026-06-23 · view certificate

$200.00

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Lab report included

MOTS-c Liquid Spray · 25mg

$200.00

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AboutLab reportSpecificationsQuestions

Finished in the USA

MOTS-c liquid spray is a 16-amino-acid mitochondrial-derived peptide studied in research for AMPK activation, insulin sensitivity. Each bottle is HPLC-verified to ≥99% purity, endotoxin-screened (<0.1 EU/mg), and formulated for laboratory research.

What Is MOTS-c Peptide?

MOTS-c (Mitochondrial Open-Reading-Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within the mitochondrial genome itself — one of the very few peptides known to originate there rather than in nuclear DNA. First characterized at the USC Leonard Davis School of Gerontology in 2015, MOTS-c acts as a mitochondrial hormone, signaling through AMPK and related metabolic pathways to regulate glucose and lipid homeostasis. Real Peptides is the first supplier to offer MOTS-c in liquid spray format — expanding research access beyond traditional injectable-only protocols.

Why Choose MOTS-c Liquid Spray?

Researchers choose MOTS-c liquid spray when studying mitochondrial-to-nuclear signaling, metabolic syndrome models, insulin resistance, exercise biology, and aging pathways. The pre-solubilized format eliminates reconstitution variability between experiments, supporting consistent concentration control across replicates. Verified ≥99% pure by HPLC with endotoxin <0.1 EU/mg.

What Sets MOTS-c Apart?

MOTS-c is the only widely-studied peptide encoded directly by mitochondrial DNA rather than the nuclear genome. That makes it a uniquely direct biological messenger between cellular energy status and nuclear gene programs — essentially, a molecular signal that bridges the cell’s power plant and its command center. Real Peptides supplies it pre-solubilized in a multi-use format, a presentation with few equivalents currently available for this compound. It’s commonly studied alongside broader mitochondrial and metabolic peptides in energy-metabolism research.

Research observations

AMPK Pathway Activation

MOTS-c activates AMP-activated protein kinase (AMPK) in myocyte and hepatocyte cultures, modeling enhanced glucose uptake and lipid oxidation.

AMPK Pathway Signaling

Endogenous MOTS-c rises approximately 12-fold in skeletal muscle after exercise. Exogenous MOTS-c administration models overlapping metabolic effects in research settings.

Lab-Friendly Format

Pre-formulated liquid spray — no reconstitution required, no injection. Store at 2–8°C, protect from light. Maintains ≥98% integrity throughout shelf life.

Test date on certificate

Arrow Lab Solutions · 1 report · 99.2% pure

CompoundMOTS-c Liquid Spray

Research areaLiquid Spray

FormatLiquid spray

Sizes25mg

Reconstituted shelf life30 days at 2–8°C

Independent laboratoryFreedom Diagnostics and Kovera

Lab reports on file1 report

Ships fromSaint Petersburg, FL and California

DispatchWithin 24 hours